Compare Vacation Rentals & Airbnb in Santa Cruz

106 available vacation rental offers

7 nights
2
1
  • airbnb
  • booking
  • vrbo
  • expedia
  • priceline
  • tripadvisor
  • tripcom
  • sonder
  • homestay
  • hostelworld
  • hotelscom
  • agoda
Santa Cruz vacation rentals
Choose the perfect vacation accommodation
Price per night
Accommodation type
Rating

106 Rentals and Airbnb in Santa Cruz

Best family friendly Santa Cruz vacation rentals

Among the 106 accommodations in Santa Cruz, here are the 4 best family friendly rentals

Intown Apart Santa Cruz - Santa Cruz
8.7 189 reviews

Intown Apart Santa Cruz

apartment, Santa Cruz
Intown is a self-catering apartment located in Santa Cruz, 35 kilometres from San Fernando and 40 kilometres from Curicó. This accommodation has received very good user ratings and excellent ratings for location and cleanliness.
The apartment has one bathroom and a kitchen equipped with a fridge, microwave, toaster, and kettle. It also offers free Wi-Fi, parking, and a concierge service, allowing guests to explore the charming town of Colchagua, just 7 kilometres away, and discover the rich history and culture of Santa Cruz.
Hermosa Cabaña A Pasos De Santa Cruz - Santa Cruz
9.9 68 reviews

Hermosa Cabaña A Pasos De Santa Cruz

cabin
This charming one-bedroom cottage is located just a 10-minute drive from the centre of Santa Cruz, nestled amongst vineyards and supermarkets. It has consistently received excellent reviews for its cleanliness, location and overall experience.
The cottage is ideal for couples seeking a peaceful retreat and can comfortably accommodate two guests. It is fully equipped with air conditioning, a swimming pool, a garden and parking, as well as a kitchen with a fridge and internet access.
Cabaña Alerce - Santa Cruz
9.6 33 reviews

Cabaña Alerce

apartment
This Santa Cruz apartment, sleeping four, is situated in [District Name - needs further information to complete this sentence accurately], requiring further details to specify proximity to local landmarks.
The 46-square-metre flat features two bedrooms, a full kitchen, living room, dining area, swimming pool access, free Wi-Fi, on-site parking, BBQ, and bike hire.
Colchagua Stay . Vive Tu Experiencia En Santa Cruz - Santa Cruz
9.9 63 reviews

Colchagua Stay . Vive Tu Experiencia En Santa Cruz

apartment
This two-bedroom apartment in the Colchagua Valley is just 3 kilometres from the casino and a short drive from restaurants, wineries, the town centre, and a supermarket. The apartment has received excellent ratings for location, cleanliness, and overall user experience.
The apartment is ideal for families or groups of up to four people. It includes a garden, internet access, a fully equipped kitchen with a fridge and freezer, and allows pets.

Best Santa Cruz vacation rentals with parking

Casa Mimbre Santa Cruz - Santa Cruz
10 3 reviews

Casa Mimbre Santa Cruz

house
This central Santa Cruz flat is located in the main district, a short walk from the Casino, the Plaza de Armas, and the Colchagua Museum.
This three-bedroom flat accommodates eight guests and features air conditioning, Wi-Fi, and a fully equipped kitchen, powered by photovoltaic panels for eco-friendly stays.
Casa Parrón - Santa Cruz
9.7 30 reviews

Casa Parrón

house
This Santa Cruz house, sleeping eight, offers three bedrooms and two bathrooms, conveniently located near various attractions; precise distances to landmarks are not provided.
The property includes parking, air conditioning, a kitchen, internet access, and is suitable for families or groups seeking comfortable self-catering accommodation.
Downtown Santa Cruz House  9 Beds  Wine Country - Santa Cruz
No reviews

Downtown Santa Cruz House 9 Beds Wine Country

apartment
This six-bedroom flat in Santa Cruz, Chile, is situated just 200 metres from the town centre, providing easy access to local amenities.
Accommodating up to 13 guests, this property offers a spacious living area, a kitchen equipped with a fridge, freezer, and microwave, and includes parking and garden access.
Tiny Cabins N° 1 (Dos Personas) Incluye Desayuno - Santa Cruz
9.9 34 reviews

Tiny Cabins N° 1 (Dos Personas) Incluye Desayuno

gîte
This premium Santa Cruz guesthouse is situated 1 kilometre from the town centre, a 10-minute drive from Colchagua Valley wineries, and 5 minutes from the Colchagua Casino & Museum.
Offering fully equipped matrimonial cabins for two, it features a swimming pool, garden, fitness centre, and includes a delicious country-style breakfast, daily housekeeping, and Wi-Fi; BBQ facilities are available for a fee.

Frequently Asked Questions about vacation rentals in Santa Cruz

  • What sports or outdoor activites can visitors enjoy in and around Santa Cruz?

    Santa Cruz is an adventure paradise! You can go trekking in the Andes, try fly fishing in the rivers, or go white-water rafting on the Baker River. There's also great kayaking and mountain biking in the area.
  • What are the best Airbnb and vacation rentals in Santa Cruz?

    Vibo Wine Lodge At Viu Manent, Como En Casa - - and Comfortable House With Swimmingpool are the most popular Airbnb and vacation rentals in Santa Cruz among travelers.

  • What amenities are commonly available in vacation rentals in Santa Cruz?

    Most vacation rentals in Santa Cruz offer basic amenities like Wi-Fi, a kitchen, and a bathroom. Some might have a fireplace, a patio, or even a hot tub. It's best to check the listing for specific amenities.
  • What are the most popular Airbnbs in Santa Cruz?

    Among the Airbnbs in Santa Cruz, Como En Casa - -, Comfortable House With Swimmingpool and Casa Madera - Diseño Y Tradición are the most popular ones.

  • What time of year is best to rent a vacation rental Santa Cruz?

    The best time to visit Santa Cruz depends on what you want to do. Summer (December to February) is the warmest and sunniest, perfect for outdoor activities. Winter (June to August) is snowy and ideal for skiing and snowboarding, though some attractions may be closed.
  • What are the best vacation rentals with a pool in Santa Cruz?

    Vibo Wine Lodge At Viu Manent, Comfortable House With Swimmingpool and El Refugio De Santa Cruz are the best vacation rentals with a pool in Santa Cruz.

  • What are the local dishes in Santa Cruz region?

    The local cuisine in Santa Cruz is hearty and influenced by the Patagonian landscape. Try the 'cordero al palo', a whole lamb roasted on a spit, or 'pastel de choclo', a savoury corn pie. You'll also find delicious seafood dishes, like 'centolla' (king crab) and 'merluza austral' (Patagonian hake).
  • What are the best rentals for families and kids in Santa Cruz?

  • What are the best rentals or Airbnbs with a jacuzzi in Santa Cruz?

    The best vacation rentals or Airbnb with a jacuzzi in Santa Cruz are Vibo Wine Lodge At Viu Manent, El Refugio De Santa Cruz and Nenquen Lodge.

Popular destinations

Best Santa Cruz vacation rentals with a balcony

Cómo En Casa Y Cerca Del Centro - Santa Cruz
No reviews

Cómo En Casa Y Cerca Del Centro

apartment, Santa Cruz
This Santa Cruz flat offers a convenient district location, providing straightforward access to the city centre and local attractions without being in the busiest areas.
This 80-square-metre flat accommodates up to nine guests, featuring one bedroom, two bathrooms, a fully equipped kitchen, a seating area with a fireplace, and a terrace, with complimentary private parking and free high-speed WiFi included.
Casa Encino Ii - Santa Cruz
No reviews

Casa Encino Ii

house, Paniahue
This holiday cottage in Paniahue is located 187 kilometres from Santiago International Airport, offering a peaceful retreat for up to 11 guests.
This 130 square metre holiday home features two bedrooms, two bathrooms, a fully equipped kitchen, free Wi-Fi, private parking, and a terrace, with a flat-screen TV for entertainment and a strictly non-smoking policy.

Best pet friendly Santa Cruz vacation rentals

Among the 106 accommodations in Santa Cruz, here are the 4 best pet friendly rentals

Tiny Cabin En Sector Hotelero - Santa Cruz
9.3 17 reviews

Tiny Cabin En Sector Hotelero

cabin
This charming cottage is situated in the Colchagua Valley, just a short drive from Santa Cruz, offering a peaceful retreat amidst rolling vineyards and picturesque countryside. The property consistently receives excellent ratings for its cleanliness, location, and overall guest experience.
The cosy cottage comfortably accommodates up to three guests and features a fully equipped kitchen, a private garden, and a swimming pool. Guests can enjoy the convenience of air conditioning, internet access, and parking, as well as explore the nearby wineries, restaurants, and attractions.
Tinny Loft House - Santa Cruz
10 1 review

Tinny Loft House

cabin
This secluded lodge in Santa Cruz offers a tranquil escape, located in a peaceful district ideal for relaxation.
This pet-friendly cabin accommodates up to three guests and features a kitchen, air conditioning, a swimming pool, jacuzzi, and sauna for a rejuvenating stay.
Casa Refugio Santa Cruz - Santa Cruz
10 1 review

Casa Refugio Santa Cruz

house
This comfortable 4-person house is located in a quiet residential area of Santa Cruz, offering convenient access to the Colchagua wine region, just a few minutes' drive from the town centre.
This self-catering apartment provides two bedrooms, one bathroom, and a fully equipped kitchen, making it an ideal base for up to four guests exploring the renowned Colchagua wine region.
Casa Sta. Cruz Valle-colch. Viñedo: Estc. Bbq Area - Santa Cruz
9.7 151 reviews

Casa Sta. Cruz Valle-colch. Viñedo: Estc. Bbq Area

house
This charming house in Santa Cruz is ideally situated just 500 metres from the casino, the Colchagua Museum, and the town centre, offering easy access to the area's cultural attractions. The property consistently receives excellent ratings for its cleanliness, location, and overall experience.
The house has three bedrooms, comfortably accommodating up to six guests, making it perfect for families or groups of friends. Guests can enjoy a fully equipped kitchen, a private garden with a fireplace and barbecue, and secure parking for two vehicles, ensuring a comfortable and enjoyable stay.
©2026 cozycozy.com