Compare Vacation Rentals & Airbnb in Seneca, SC

This Seneca waterfront property, situated within 3.2km of Lake Keowee and close to Norton-Thompson Park and Walnut Street Park, offers stunning lake views.
This four-bedroom, three-bathroom house sleeps eight guests and boasts a fully equipped kitchen, free Wi-Fi, a terrace, garden, parking, and barbecue facilities; nearby attractions include Wyndham Plaza and Gignilliat Community Centre.

This studio apartment is located on Lake Hartwell, just 10km from Clemson, South Carolina and close to the southern Appalachian mountains, offering a peaceful retreat in a beautiful natural setting. It has received excellent ratings for location, cleanliness and overall experience from previous guests.
The studio is ideal for a couple or small family, with a king-size bed and a comfortable living space. Guests can enjoy access to kayaks, a canoe and a stand-up paddleboard, explore the food forest, and benefit from the unique eco-friendly features, including a composting toilet and on-demand hot water heater.

This lakefront property is situated just 20 kilometres from the centre of Clemson, offering a tranquil escape with easy access to the university and its surroundings. The apartment has received excellent reviews from previous guests, highlighting its comfortable and well-equipped nature.
The spacious apartment, spanning 437 square metres, comfortably accommodates up to 18 guests across its five bedrooms and five bathrooms. Enjoy a range of amenities including a fully equipped kitchen, a Jacuzzi, a garden, and a private dock with access to Lake Keowee, perfect for relaxing and enjoying water sports.

This waterfront chalet is located in Seneca, South Carolina, just a short distance from grocery stores, restaurants, and other amenities. It has an excellent user rating, making it a popular choice for travellers.
The chalet has four bedrooms, three bathrooms, and sleeps up to eight guests in 135 square metres of space. It features a private boat dock, a spacious garden, a large terrace with stunning lake views, and modern amenities including air conditioning, a fully equipped kitchen, and internet access.

This loft-style apartment is located in historic downtown Seneca, providing walkable access to shops, restaurants, and coffee spots, and is a short drive to Lake Keowee and Clemson University.
This one-bedroom, one-bathroom flat accommodates up to four guests, featuring a full kitchen with a microwave oven and dishwasher, air conditioning, and an in-unit washer/dryer combo.

This exclusive lakefront holiday let in Seneca offers a peaceful retreat in a quiet cove on Lake Hartwell, featuring a private dock and stunning water views, located just 24 kilometres from Clemson University.
This family-friendly apartment sleeps eight guests across three bedrooms and two bathrooms, boasting a fully equipped kitchen with a dishwasher, air conditioning, a garden, parking, and a finished basement with a pool table, plus on-site kayaks and paddle boards for enjoying the lake.

This lakeside cottage near Lake Keowee is a 32km drive from Clemson University, offering convenient access to both the university and Seneca’s amenities.
The self-catering property sleeps four, featuring a queen-size sofa bed, a loft with twin beds (or a king-size option), a fully equipped kitchen with a fridge, air conditioning, Wi-Fi, and a private dock on Lake Keowee ideal for fishing.

This Seneca holiday home, near Lake Keowee, offers easy access to the marina and is a 32km drive from Clemson University.
The 149 square metre property sleeps six, boasting three bedrooms, two bathrooms, a fully equipped kitchen (including dishwasher), a garden, tennis court, parking, and internet access; plus nearby opportunities for watersports such as jet skiing and kayaking.

This waterfront property is situated just 160 metres from Lake Keowee, a short drive from Keowee Key Golf Course and Art Circle Gallery, both located 14.5 kilometres away. The property enjoys excellent user ratings and offers a comfortable and convenient stay for travellers visiting Seneca.
This 3-bedroom house spans 260 square metres and comfortably accommodates up to 10 guests. The house features a fully equipped kitchen, a terrace, a garden, and parking facilities, providing everything you need for a relaxing and enjoyable stay.

This lakefront holiday home in Seneca offers direct access to Lake Keowee and is situated 11.7 kilometres from Clemson Memorial Stadium.
This spacious property features three bedrooms, three bathrooms, a fully equipped kitchen with a dishwasher, complimentary WiFi, and on-site water sports facilities, accommodating up to fifteen guests.

This waterfront holiday home is situated just 0.16 kilometres from Lake Keowee, within a 24-kilometre drive of both the Art Circle Gallery and Keowee Reservoir. The property has consistently received excellent ratings for its location, cleanliness, and overall user experience.
This spacious house has seven bedrooms and seven bathrooms, comfortably accommodating up to 14 guests. Enjoy a range of amenities including a fully equipped kitchen, a terrace, a garden, parking, and a fireplace, as well as access to a washing machine, a refrigerator, and a television.

This Seneca holiday home is situated 5.5km from Clemson Memorial Stadium and 72km from Greenville-Spartanburg International Airport.
The 149 square metre property boasts three bedrooms, two bathrooms, sleeps eleven guests, and includes a fully equipped kitchen, screened patio, washing machine, free Wi-Fi, and air conditioning.

This Seneca holiday home, a 130 square metre apartment, is located a 0.8 km walk from the Shaver Recreation Complex and a short 5-minute drive from Lake Keowee.
The three-bedroom, two-bathroom property sleeps six guests and boasts a private garden, terrace, fire pit, barbecue, fully equipped kitchen, in-unit laundry, air conditioning, and free on-site parking.

This Seneca lakefront apartment, situated 16km from Clemson, offers easy access to Lake Keowee Marina and local amenities.
Sleeping eight guests, this four-bedroom, two-bathroom dwelling boasts a fully equipped kitchen, terrace, garden, Wi-Fi, smart TV, and access to a community dock perfect for swimming, fishing and kayaking; an outdoor fire pit completes the property.

This lakefront house is located in a quiet cul-de-sac in Coneross Creek, just 24 kilometres from Clemson University and 10 kilometres from the Friendship Boat Ramp. The property has received excellent ratings for its location, cleanliness and overall user experience.
This spacious home spans 167 square metres and comfortably sleeps up to 10 guests in its three bedrooms and two bathrooms. Guests can enjoy a range of amenities including a private dock with power and lights, a swimming pool, a fitness centre, and a pool table, as well as access to a canoe, paddle boat, kayaks, and life jackets for exploring the lake.

This new 2024-built apartment, situated on Lake Hartwell approximately 24 kilometres from Clemson University and Seneca town centre, offers seclusion and lake views.
The one-bedroom, one-bathroom dwelling sleeps three guests and includes a fully equipped kitchen, private dock with canoes and paddleboards, pet amenities, and a fire pit; family amenities are available on request.