Hotels in Santee, SC

34 available hotel offers

2 nights
2
1
  • airbnb
  • booking
  • vrbo
  • expedia
  • premierinn
  • sykescottages
  • plumguide
  • hotelscom
  • tripadvisor
  • homestay
  • tuivillas
  • hostelworld
Santee, SC hotels
Choose the perfect holiday accommodation
Price per night
Accommodation type
Rating

34 Cheap hotels in Santee, SC

Browse Family-Friendly Hotels in Santee, SC

Getting the hotel right makes all the difference on a family trip to Santee, SC, with city attractions within easy reach from these selected stays. Start comparing now.

Fairfield Inn & Suites Santee - Santee, SC
9.7 1361 reviews
Santee, SC
14/08 – 20/08
£119/nighttotal: Â£714 (6 )

Fairfield Inn & Suites Santee

1 2
hotel , Santee
The Fairfield Inn & Suites Santee is in Santee, South Carolina, a short distance from the town centre and close to local attractions. This 3-star hotel is rated excellent by previous guests. The hotel is family-friendly and welcomes pets.
The Fairfield Inn & Suites Santee offers a range of amenities for guests, including an outdoor swimming pool, a fitness centre, a shared lounge, and a snack bar. There are also complimentary bikes available to explore the local area.
Holiday Inn Santee By Ihg - Santee, SC
8.1 94 reviews
Santee, SC
19/06 – 21/06
£132/nighttotal: Â£264 (2 )

Holiday Inn Santee By Ihg

1 2
hotel , Santee
The Holiday Inn Santee, An Ihg Hotel is situated just off the I-95 in Santee, South Carolina, less than 80 kilometres from both Columbia and Charleston. This family-friendly hotel offers a range of amenities including a heated swimming pool, a restaurant and a fitness centre, as well as pet-friendly accommodation for those travelling with their furry companions.
Hampton Inn Santee-i-95 - Santee, SC
9.4 2137 reviews
Santee, SC
08/07 – 22/07
£144/nighttotal: Â£2016 (14 )

Hampton Inn Santee-i-95

1 2
hotel , Santee
The Hampton Inn Santee-i-95 is conveniently situated just off Interstate 95, a short drive from Lake Marion and the Elloree Heritage Museum. This 3-star hotel consistently receives excellent user ratings for its cleanliness, location, and overall experience.
The accommodation offers a range of features for a comfortable stay, including a swimming pool, Jacuzzi, fitness centre, and a complimentary breakfast. Guests can also enjoy the on-site restaurant and relax in the garden or on the terrace.
Comfort Inn & Suites Santee I-95 - Santee, SC
8.0 1939 reviews
Santee, SC
14/08 – 20/08
£96/nighttotal: Â£576 (6 )

Comfort Inn & Suites Santee I-95

1 2
hotel , Santee
The Comfort Inn & Suites Santee I-95 is conveniently located off the I-95 in Santee, approximately 88.5 kilometres from Charleston International Airport.
This family-friendly hotel offers a seasonal outdoor swimming pool, complimentary WiFi, a business centre, and a fitness centre, with guest rooms featuring a seating area, television, and fridge.

Discover Hotels with a Swimming Pool in Santee, SC

These hotels in Santee, SC include a pool, so a proper swim in the heart of the city is always an option during your stay.

Fairfield Inn & Suites Santee - Santee, SC
9.7 1361 reviews
Santee, SC
14/08 – 20/08
£119/nighttotal: Â£714 (6 )

Fairfield Inn & Suites Santee

1 2
hotel , Santee
The Fairfield Inn & Suites Santee is in Santee, South Carolina, a short distance from the town centre and close to local attractions. This 3-star hotel is rated excellent by previous guests. The hotel is family-friendly and welcomes pets.
The Fairfield Inn & Suites Santee offers a range of amenities for guests, including an outdoor swimming pool, a fitness centre, a shared lounge, and a snack bar. There are also complimentary bikes available to explore the local area.
Best Western Plus Santee Inn - Santee, SC
8.7 1543 reviews
Santee, SC
10/07 – 11/07
£232/nightfor 1 night

Best Western Plus Santee Inn

2 8
hotel , Santee
The Best Western Plus Santee Inn is located in Santee, South Carolina, around an hour's drive from Charleston International Airport. It's a 3-star hotel that has received very good user ratings, making it a popular choice for travellers visiting the area.
The hotel offers a variety of comfortable rooms with private bathrooms and free Wi-Fi. Guests can enjoy a refreshing swim in the outdoor pool, relax in the garden, or grab a bite to eat at the on-site restaurant and bar.
Comfort Inn & Suites Santee I-95 - Santee, SC
8.0 1939 reviews
Santee, SC
14/08 – 20/08
£96/nighttotal: Â£576 (6 )

Comfort Inn & Suites Santee I-95

1 2
hotel , Santee
The Comfort Inn & Suites Santee I-95 is conveniently located off the I-95 in Santee, approximately 88.5 kilometres from Charleston International Airport.
This family-friendly hotel offers a seasonal outdoor swimming pool, complimentary WiFi, a business centre, and a fitness centre, with guest rooms featuring a seating area, television, and fridge.
Lakeside Bliss: 2br Suite At Wyndham Lake Marion - Santee, SC
10 4 reviews
Santee, SC
14/08 – 20/08
£179/nighttotal: Â£1074 (6 )

Lakeside Bliss: 2br Suite At Wyndham Lake Marion

2 2
hotel , Santee
This Santee lakeside guesthouse, part of Wyndham Lake Marion within Ballards Pointe Resort & Marina, offers direct access to Lake Marion for boating and fishing.
The two-bedroom, two-bathroom suite sleeps up to six guests and includes a full kitchen, in-unit laundry, a swimming pool, fitness centre, and barbecue and picnic areas within the resort.

Frequently asked questions about hotels in Santee, SC

  • How can travelers relax during a week in and arond Santee, SC?

    Santee is all about slowing down and enjoying the peace and quiet. Take a boat trip on Lake Marion, go for a swim in the Santee River, or simply relax on the porch of your hotel or cabin and soak in the tranquility of the surroundings.
  • What are the best hotels with a swimming pool in Santee, SC?

    Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn are among the best hotels with a swimming pool in Santee, SC.

  • What amenities can travelers expect in hotel rooms in Santee, SC?

    Most hotels in Santee offer basic amenities like air conditioning, Wi-Fi, and cable TV. Some may also have swimming pools, hot tubs, and fitness centres. You can also find a few charming bed and breakfasts with unique amenities like fireplaces and private balconies.
  • What are the most popular 2, 3 and 4-star hotels in Santee, SC?

    Among 2, 3 and 4-star hotels in Santee, SC, Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn are the most popular ones.

  • When is the best time to book a hotel in Santee, SC?

    The best time to book a hotel in Santee is during the shoulder seasons, from April to May or September to October. You'll enjoy pleasant weather and fewer crowds, making it a great time to explore the area.
  • What are the best family friendly hotels in Santee, SC?

    The best family friendly hotels in Santee, SC are Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Comfort Inn & Suites Santee I-95.

  • Which towns or cities worth a visit near Santee, SC?

    Just a short drive from Santee, you can visit the charming town of Manning, known for its historic architecture and friendly atmosphere. You can also explore the city of Sumter, which offers a variety of museums, art galleries, and shopping options.
  • What are the best pet friendly hotels in Santee, SC?

    The best pet friendly hotels in Santee, SC are Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn.

  • What are the best hotels with jacuzzi in Santee, SC?

    Hampton Inn Santee-i-95, Super 8 By Wyndham Santee and The Merry Inn @ Lake Marion are the best hotels with a jacuzzi in Santee, SC.

Destinations nearby

Compare Hotels with Breakfast Included in Santee, SC

Choosing a hotel with breakfast included in Santee, SC ensures every day of sightseeing starts on the right note.

Best Western Plus Santee Inn - Santee, SC
8.7 1543 reviews
Santee, SC
10/07 – 11/07
£232/nightfor 1 night

Best Western Plus Santee Inn

2 8
hotel , Santee
The Best Western Plus Santee Inn is located in Santee, South Carolina, around an hour's drive from Charleston International Airport. It's a 3-star hotel that has received very good user ratings, making it a popular choice for travellers visiting the area.
The hotel offers a variety of comfortable rooms with private bathrooms and free Wi-Fi. Guests can enjoy a refreshing swim in the outdoor pool, relax in the garden, or grab a bite to eat at the on-site restaurant and bar.
Comfort Inn & Suites Santee I-95 - Santee, SC
8.0 1939 reviews
Santee, SC
14/08 – 20/08
£96/nighttotal: Â£576 (6 )

Comfort Inn & Suites Santee I-95

1 2
hotel , Santee
The Comfort Inn & Suites Santee I-95 is conveniently located off the I-95 in Santee, approximately 88.5 kilometres from Charleston International Airport.
This family-friendly hotel offers a seasonal outdoor swimming pool, complimentary WiFi, a business centre, and a fitness centre, with guest rooms featuring a seating area, television, and fridge.
Holiday Inn Santee By Ihg - Santee, SC
8.1 94 reviews
Santee, SC
19/06 – 21/06
£132/nighttotal: Â£264 (2 )

Holiday Inn Santee By Ihg

1 2
hotel , Santee
The Holiday Inn Santee, An Ihg Hotel is situated just off the I-95 in Santee, South Carolina, less than 80 kilometres from both Columbia and Charleston. This family-friendly hotel offers a range of amenities including a heated swimming pool, a restaurant and a fitness centre, as well as pet-friendly accommodation for those travelling with their furry companions.
Hampton Inn Santee-i-95 - Santee, SC
9.4 2137 reviews
Santee, SC
08/07 – 22/07
£144/nighttotal: Â£2016 (14 )

Hampton Inn Santee-i-95

1 2
hotel , Santee
The Hampton Inn Santee-i-95 is conveniently situated just off Interstate 95, a short drive from Lake Marion and the Elloree Heritage Museum. This 3-star hotel consistently receives excellent user ratings for its cleanliness, location, and overall experience.
The accommodation offers a range of features for a comfortable stay, including a swimming pool, Jacuzzi, fitness centre, and a complimentary breakfast. Guests can also enjoy the on-site restaurant and relax in the garden or on the terrace.

Popular Hotels with Parking in Santee, SC

Free on-site parking comes with these hotels in Santee, SC, allowing you to focus on the city centre from day one.

Quality Inn & Suites Santee I-95 - Santee, SC
Santee, SC
20/06 – 27/06
£53/nighttotal: Â£371 (7 )

Quality Inn & Suites Santee I-95

1 2
hotel , Santee
The Quality Inn & Suites is located in Santee, just a short walk from the town centre and close to both the Santee Cooper Country Club and Santee National Golf Club. This 2-star hotel is a good option for travellers looking for a comfortable and convenient base to explore the area.
The hotel offers a range of amenities, including free Wi-Fi, an outdoor pool, and free parking. Guests can also enjoy laundry facilities and the convenience of being able to walk to nearby attractions.
Fairfield Inn & Suites Santee - Santee, SC
9.7 1361 reviews
Santee, SC
14/08 – 20/08
£119/nighttotal: Â£714 (6 )

Fairfield Inn & Suites Santee

1 2
hotel , Santee
The Fairfield Inn & Suites Santee is in Santee, South Carolina, a short distance from the town centre and close to local attractions. This 3-star hotel is rated excellent by previous guests. The hotel is family-friendly and welcomes pets.
The Fairfield Inn & Suites Santee offers a range of amenities for guests, including an outdoor swimming pool, a fitness centre, a shared lounge, and a snack bar. There are also complimentary bikes available to explore the local area.
Tru By Hilton Santee - Santee, SC
8.9 1542 reviews
Santee, SC
10/07 – 11/07
£276/nightfor 1 night

Tru By Hilton Santee

2 8
hotel , Santee
The Tru By Hilton Santee is located just a short distance from Santee Cooper Country Club, Santee Outlets, and Santee State Park, making it a convenient base for exploring the area. This 2.5-star hotel has consistently received excellent user ratings, indicating a positive experience for previous guests.
The accommodation offers a range of amenities to ensure a comfortable stay, including a swimming pool, a fitness centre, and free parking. Guests can also enjoy free Wi-Fi in public areas and benefit from a 24-hour front desk for added convenience.
Best Western Plus Santee Inn - Santee, SC
8.7 1543 reviews
Santee, SC
10/07 – 11/07
£232/nightfor 1 night

Best Western Plus Santee Inn

2 8
hotel , Santee
The Best Western Plus Santee Inn is located in Santee, South Carolina, around an hour's drive from Charleston International Airport. It's a 3-star hotel that has received very good user ratings, making it a popular choice for travellers visiting the area.
The hotel offers a variety of comfortable rooms with private bathrooms and free Wi-Fi. Guests can enjoy a refreshing swim in the outdoor pool, relax in the garden, or grab a bite to eat at the on-site restaurant and bar.
©2026 cozycozy.com