Hotels in Santee, SC

30 available hotel offers

2 nights
2
1
  • airbnb
  • booking
  • vrbo
  • expedia
  • premierinn
  • sykescottages
  • plumguide
  • hotelscom
  • tripadvisor
  • homestay
  • tuivillas
  • hostelworld
Santee, SC hotels
Choose the perfect holiday accommodation
Price per night
Accommodation type
Rating

30 Cheap hotels in Santee, SC

Best Santee, SC hotels for families

Fairfield By Marriott Inn & Suites Santee - Santee, SC
No reviews

Fairfield By Marriott Inn & Suites Santee

hotel, Santee
The Fairfield Inn & Suites by Marriott Santee is conveniently located near the Santee Cooper Lakes and within easy driving distance of the Santee National Wildlife Refuge, making it an ideal base for exploring the area's natural beauty. This 2.5-star hotel offers comfortable and well-equipped rooms.
The hotel features a modern design with stylish decor and comfortable furnishings. It also offers a range of amenities, including a swimming pool, fitness centre, and complimentary breakfast, catering to various needs and preferences.
Hampton Inn Santee-i-95 - Santee, SC
9.5 2127 reviews

Hampton Inn Santee-i-95

hotel, Santee
The Hampton Inn Santee-i-95 is conveniently situated just off Interstate 95, a short drive from Lake Marion and the Elloree Heritage Museum. This 3-star hotel consistently receives excellent user ratings for its cleanliness, location, and overall experience.
The accommodation offers a range of features for a comfortable stay, including a swimming pool, Jacuzzi, fitness centre, and a complimentary breakfast. Guests can also enjoy the on-site restaurant and relax in the garden or on the terrace.
Fairfield Inn & Suites Santee - Santee, SC
9.7 1354 reviews

Fairfield Inn & Suites Santee

hotel, Santee
The Fairfield Inn & Suites Santee is in Santee, South Carolina, a short distance from the town centre and close to local attractions. This 3-star hotel is rated excellent by previous guests. The hotel is family-friendly and welcomes pets.
The Fairfield Inn & Suites Santee offers a range of amenities for guests, including an outdoor swimming pool, a fitness centre, a shared lounge, and a snack bar. There are also complimentary bikes available to explore the local area.
Holiday Inn Santee By Ihg - Santee, SC
8.1 1408 reviews

Holiday Inn Santee By Ihg

hotel, Santee
The Holiday Inn Santee By IHG is situated in Santee, placing guests within 1.6 kilometres of Santee Cooper Country Club and Santee State Park, and within 9.7 kilometres of Lake Marion.
This 3-star hotel offers a range of amenities including an indoor swimming pool, a 24-hour fitness centre, complimentary WiFi in public areas, and free self-parking, with a bar/lounge and business centre also available.

Best Santee, SC hotels with a pool

Among the 30 accommodations in Santee, SC, here are the 4 best hotels with a pool

Fairfield By Marriott Inn & Suites Santee - Santee, SC
No reviews

Fairfield By Marriott Inn & Suites Santee

hotel, Santee
The Fairfield Inn & Suites by Marriott Santee is conveniently located near the Santee Cooper Lakes and within easy driving distance of the Santee National Wildlife Refuge, making it an ideal base for exploring the area's natural beauty. This 2.5-star hotel offers comfortable and well-equipped rooms.
The hotel features a modern design with stylish decor and comfortable furnishings. It also offers a range of amenities, including a swimming pool, fitness centre, and complimentary breakfast, catering to various needs and preferences.
Comfort Inn & Suites Santee I-95 - Santee, SC
8.0 1953 reviews

Comfort Inn & Suites Santee I-95

hotel, Santee
The Comfort Inn & Suites Santee I-95 is conveniently located off the I-95 in Santee, approximately 88.5 kilometres from Charleston International Airport.
This family-friendly hotel offers a seasonal outdoor swimming pool, complimentary WiFi, a business centre, and a fitness centre, with guest rooms featuring a seating area, television, and fridge.
Holiday Inn Santee By Ihg - Santee, SC
8.1 1408 reviews

Holiday Inn Santee By Ihg

hotel, Santee
The Holiday Inn Santee By IHG is situated in Santee, placing guests within 1.6 kilometres of Santee Cooper Country Club and Santee State Park, and within 9.7 kilometres of Lake Marion.
This 3-star hotel offers a range of amenities including an indoor swimming pool, a 24-hour fitness centre, complimentary WiFi in public areas, and free self-parking, with a bar/lounge and business centre also available.
Hampton Inn Santee-i-95 - Santee, SC
9.5 2127 reviews

Hampton Inn Santee-i-95

hotel, Santee
The Hampton Inn Santee-i-95 is conveniently situated just off Interstate 95, a short drive from Lake Marion and the Elloree Heritage Museum. This 3-star hotel consistently receives excellent user ratings for its cleanliness, location, and overall experience.
The accommodation offers a range of features for a comfortable stay, including a swimming pool, Jacuzzi, fitness centre, and a complimentary breakfast. Guests can also enjoy the on-site restaurant and relax in the garden or on the terrace.

Frequently asked questions about hotels in Santee, SC

  • What are the most affordable attractions in and around Santee, SC?

    For a budget-friendly day out, head to the Santee National Wildlife Refuge. You can enjoy hiking, birdwatching, and fishing for free. The Santee Coastal Reserve is also a great option for a nature walk.
  • What are the best hotels with a swimming pool in Santee, SC?

    Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn are among the best hotels with a swimming pool in Santee, SC.

  • How can travelers relax during a week in and arond Santee, SC?

    Santee is all about relaxation! Spend your days fishing on Lake Marion or Lake Moultrie, or simply unwind on the sandy shores of one of the many beaches. The Santee Cooper Lakes offer plenty of opportunities for kayaking and canoeing too.
  • What are the most popular 2, 3 and 4-star hotels in Santee, SC?

    Among 2, 3 and 4-star hotels in Santee, SC, Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn are the most popular ones.

  • What amenities can travelers expect in hotel rooms in Santee, SC?

    Most hotels in Santee offer basic amenities like air conditioning, Wi-Fi, and cable TV. Some may also have swimming pools and breakfast included. You can find more luxurious options with spa facilities and fine dining in nearby towns.
  • What are the best family friendly hotels in Santee, SC?

    The best family friendly hotels in Santee, SC are Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Comfort Inn & Suites Santee I-95.

  • When is the best time to book a hotel in Santee, SC?

    The best time to book a hotel in Santee is during the shoulder seasons, from April to May and September to October. You'll find lower prices and fewer crowds during these months.
  • What are the best pet friendly hotels in Santee, SC?

    The best pet friendly hotels in Santee, SC are Fairfield Inn & Suites Santee, Hampton Inn Santee-i-95 and Best Western Plus Santee Inn.

  • What are some pet-friendly activities in and around Santee, SC?

    The Santee National Wildlife Refuge is a great place to take your furry friend for a walk. You can also enjoy a picnic at the Santee Coastal Reserve, which is pet-friendly.
  • What are the best hotels with jacuzzi in Santee, SC?

    Hampton Inn Santee-i-95, Super 8 By Wyndham Santee and The Merry Inn @ Lake Marion are the best hotels with a jacuzzi in Santee, SC.

  • Which towns or cities worth a visit near Santee, SC?

    Sumter is a charming town about 45 minutes away, known for its historic downtown and the Sumter County Museum. If you're looking for a bigger city, Charleston is about a two-hour drive from Santee and offers a vibrant mix of history, culture, and cuisine.

Popular destinations

Best Santee, SC hotels with breakfast

Among the 30 accommodations in Santee, SC, here are the 1 best hotels with breakfast

Holiday Inn Santee By Ihg - Santee, SC
8.2 89 reviews

Holiday Inn Santee By Ihg

hotel, Santee
The Holiday Inn Santee, An Ihg Hotel is situated just off the I-95 in Santee, South Carolina, less than 80 kilometres from both Columbia and Charleston. This family-friendly hotel offers a range of amenities including a heated swimming pool, a restaurant and a fitness centre, as well as pet-friendly accommodation for those travelling with their furry companions.

Best Santee, SC hotels with parking

Fairfield Inn And Suites By Marriott Santee - Santee, SC
No reviews

Fairfield Inn And Suites By Marriott Santee

hotel, Santee
The Fairfield Inn and Suites by Marriott Santee offers convenient accommodation directly off I-95 Exit 98, placing guests within easy reach of Santee Cooper Country Club, Santee National Golf Club, and Santee State Park.
This establishment provides a hearty breakfast, including an expanded hot menu and a variety of fresh options, alongside complimentary parking for guests.
©2026 cozycozy.com