Compare vacation rentals in Seneca, SC from 100+ sites!

This waterfront cabin is located near Seneca, South Carolina, just 15 kilometers from three popular lakes: Lake Keowee, Keowee Reservoir, and Lake Hartwell. Guests have consistently rated this property excellent for its location, cleanliness, and overall experience.
The two-bedroom cabin can comfortably accommodate up to five guests. Enjoy modern amenities like free Wi-Fi, a Smart TV, and a fully equipped kitchenette, along with outdoor features like a garden and barbecue grills.

This charming cottage is located near Walhalla, South Carolina, just a short drive from Walmart, Oconee Memorial Hospital, and Clemson University. It has consistently received excellent ratings for its cleanliness, location, and overall experience.
The cottage offers one bedroom and one bathroom, comfortably accommodating up to four guests. You'll enjoy a fully equipped kitchen, air conditioning, a private garden, and a peaceful fishing pond on the property.

This Seneca vacation rental, near Lake Keowee and a short walk from the marina, offers easy access to downtown Seneca and is a 20-minute drive from Clemson University.
This 1600-square-foot home features three bedrooms, two bathrooms, sleeps six, and includes a fully equipped kitchen, air conditioning, a garden, tennis court, parking, and on-site game room.

This waterfront tiny home in Martin, Georgia, offers direct access to Lake Hartwell with a private boat dock, situated only a few hundred yards from a public boat ramp.
This cozy 1-bedroom, 1-bathroom dwelling spans 580 square feet and accommodates up to two guests, featuring a kitchen with a fridge and microwave, air conditioning, WiFi, a smart TV, and a terrace or balcony on a 0.34-acre lot, with a dog-friendly policy for one dog under 20 lbs for an additional fee.

This two-bedroom, two-bathroom townhome is located in Seneca, South Carolina, minutes from downtown Seneca and a short drive to Clemson University and Clemson Memorial Stadium.
The single-story property offers a fully equipped kitchen, in-unit laundry, a private patio, free driveway parking, and comfortably accommodates four guests, with easy access to Lake Hartwell and Lake Keowee.

This charming bungalow is located in downtown Seneca, just two blocks from Ram Cat Alley, a bustling shopping and dining district, and a 10-minute drive from Clemson University's stadium. This well-rated home is perfect for families or small groups looking for a peaceful retreat. This cozy cottage has two bedrooms and one bathroom, comfortably accommodating up to four guests. Enjoy modern amenities like air conditioning, internet, and a fully equipped kitchen, as well as a peaceful garden and easy access to nearby lakes for swimming, boating, and fishing.

This Seneca vacation home, seven miles from Clemson Memorial Stadium and 48 miles from Greenville-Spartanburg International Airport, offers convenient access to local attractions.
The 1600-square-foot house features three bedrooms, two bathrooms, sleeps eleven guests, and includes amenities such as a fully equipped kitchen, private balcony, table tennis, outdoor fireplace, free Wi-Fi, and free private parking.

This Seneca, South Carolina rental is located 7.6 miles from Clemson University's main campus, offering easy access to campus events and activities.
This two-story house features two bedrooms (one king, one with extra-long twin beds), one bathroom, a spacious gathering room with a shuffleboard table and putting green, a private lower-level entrance, and kayaks for guest use, accommodating up to four guests.

This secluded lakeside cottage is located in a private wooded cove, offering easy shoreline access and is just minutes from Clemson University and Memorial Stadium.
This cabin accommodates up to 6 guests and features a spacious deck with outdoor seating, a BBQ grill, fire pit, well-equipped kitchen, and reliable Wi-Fi.

This Seneca, South Carolina cabin offers a secluded retreat amidst trees and open fields, providing stunning wildlife views.
The 2-bedroom, 2-bathroom house sleeps 4 guests and features a kitchen with a fridge, microwave, and dishwasher; a hot tub; a fireplace; and a fire pit, perfect for enjoying the outdoors.

This Seneca lakefront apartment is located just 5 minutes from Friendship Boat Landing and 20 minutes from Clemson and Anderson, making it a convenient base for exploring the area. It has consistently received excellent ratings for its cleanliness, location, and overall experience.
This 2-bedroom apartment comfortably accommodates 4 guests and features a fully equipped kitchen, a spacious living area, and a private patio with a fire pit and dock. Enjoy fishing, swimming, boating, or simply relaxing by the lake with amenities like a gas grill, high-speed internet, and entertainment options like a smart TV and Nintendo Switch.

This Seneca house rental is centrally located between Seneca and Clemson, SC, a five-minute drive from Ram Cat Alley and ten minutes from Clemson University, offering easy access to lakes, hiking trails, and local attractions.
This one-bedroom, one-bathroom dwelling sleeps six guests and boasts amenities including air conditioning, internet, parking, and a full kitchen; enjoy nearby water activities on Lakes Jocassee, Keowee, and Hartwell.